Biochemistry Final Year Project Research Topics

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1 P390321
EFFECTS OF KOLAVIRON ON LYMPHOCYTES PROLIFERATION, EXPRESSION OF TOLL LIKE RECEPTOR-2 AND VASCULAR ENDOTHELIAL GROWTH FACTOR-C GENES IN WUCHERERIA BAN...
ABSTRACT The anti proliferative effect and down regulation of vascular endothelial growth factor C and toll like receptor 2 by kolaviron rich portion of Garcinia kola on Wuchereria bancrofti infected blood were investigated. Blood samples were collected from consenting volunteers in Talata mafara, Zamfara State, Nigeria, between the hours of 10pm to 12am, stained with Giemsa and viewed microscopic... Continue Reading »

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2 P733472
BACTERIOLOGICAL EXAMINATION OF PALM WINE SOLD AT UDI LOCAL GOVERNMENT AREA
ABSTRACT This work shows how to identify the various microorganism in palm wine and how to isolate the pathogenic organism in palm wine vie Nkwuenu and the attributes were identification of bacteria and yeasts in fresh palm wine sample gave rise to the isolation of eight bacteria: Staphylococcus aureus, Escherichia coli, Lactobacillus spp, Micrococcus luteus, Serratia marcessens, Acetobacter spp, ... Continue Reading »

Item Type & Format: Project Material - Ms Word |  52 pages |  Instant Download  |  Chapter 1-5  |  BIOCHEMISTRY DEPARTMENT

3 P468644
ASSESSMENT OF THE RELATIONSHIP BETWEEN FOETAL HAEMOGLOBIN LEVELS, MARKERS OF TISSUE DESTRUCTION AND DISEASE SEVERITY IN INDIVIDUALS WITH SICKLE CELL ...
ABSTRACT Sickle cell Anaemia is a genetic disorder that leads to the production of Sickle haemoglobin, whichresults in abnormal functions of the red blood cell under hypoxic conditions.The aim of this study was to assess the relationship between Foetal haemoglobin, markers of tissue destruction and disease severity among individuals with sickle cell anaemia. Thirty seven adults with sickle cell an... Continue Reading »

Item Type & Format: Project Material - Ms Word |  72 pages |  Instant Download  |  Chapter 1-5  |  BIOCHEMISTRY DEPARTMENT

4 P974348
EFFECTS OF ETHANOLIC ROOT EXTRACT OF JATROPHA TANJORENSIS ON LIPID PROFILE OF FEMALE ALBINO WISTAR RAT
ABSTRACT This research work was carried out to determine the effects of ethanolic root extract of Jatropha tanjorensis on lipid profile of female albino wistar rats. Twenty (20) albino wistar rats weighing between 151 225 g were divided into 4 groups of 5 animals per group based on body weight. Group 1 was the normal control and was fed with distilled water and normal rat feed. Groups 2, 3 and 4 w... Continue Reading »

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5 P883519
EFFECT OF PROCESSING (TOASTING AND FERMENTATION) ON THE NUTRITIONAL VALUE OF SICKLE POD (SENNA OBTUSIFOLIA) SEEDS
ABSTRACT The effects of fermentation and toasting on the nutrients and antinutrients composition of Senna obtusifoliai seeds were investigated. Senna obtusifolia seeds were fermented with Aspergillus niger at an ambient (27 30°C) temperature for five days. Senna obtusifolia seeds were also toasted at 80oC in open pan using hot plate for 10 min. Raw Senna obtusifolia seeds contained 7.45mg/100g... Continue Reading »

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6 P395669
EFFECTS OF SELENIUM TOXICITY AND DEFICIENCY ON HUMANS
CHAPTER ONE INTRODUCTION 1.1. BACKGROUND INFORMATION Selenium (Se) is an essential trace element having biological functions of utmost importance for human health. Different from the other (semi) metals, it is incorporated into proteins by a co translational mechanism as part of the amino acid selenocysteine (SeCys), the 21st amino acid used for protein synthesis in humans, whereas only a few of t... Continue Reading »

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7 P452142
AMELIORATING ROLE OF N.P.K. FERTILIZER ON THE TOXIC EFFECTS OF NI ON (SORGHUM) ROOT ANTIOXIDANT ENZYMES
ABSTRACT This study investigated the activities of superoxide dismutase (SOD), catalase (CAT), glutothione peroxidase (GP) and the level of malondialdehyde (MDA) in the root of sorghum grown in soils contaminated with 30ppm nickel, 30ppm nickel +20ppm fertilizer and 30ppm nickel + 40ppm fertilizer. Sixty sorghum seeds were germinated in these contaminated soils and were harvested after 2 weeks, 3 ... Continue Reading »

Item Type & Format: Project Material - Ms Word |  52 pages |  Instant Download  |  Chapter 1-5  |  BIOCHEMISTRY DEPARTMENT

8 P256359
EFFECTS OF BITTER LEAF SOUP WITH GARRI ON BLOOD GLUCOSE AND GROWTH PERFORMANCES OF TYPE ONESTZ [STREPTOZOCIN] INDUCED DIABETIC RATS
A RESEARCH PROJECT ABSTRACT The antidiabetic effect of bitter leaf soup with garri on blood glucose and growth performances of type 1 streptozocin induced rats was evaluated in this work.The effect of bitter leaf soup was investigated against type 1 streptozocin induced diabetic rats. The phytochemical screening of this plant revealed the presence of the following; Alkaloids, glycosides, tannins, ... Continue Reading »

Item Type & Format: Project Material - Ms Word |  41 pages |  Instant Download  |  Chapter 1-5  |  BIOCHEMISTRY DEPARTMENT

9 P557540
MODULATION OF HIGH FRUCTOSE FED, STREPTOZOTOCIN-INDUCED TYPE 2 DIABETES BY WONDERFUL KOLA (BUCHHOLZIA CORIACEA) SEED EXTRACTS IN MALE WISTAR RATS
ABSTRACT Type 2 diabetes (T2D) occurs when there is an advanced determent in insulin action (insulin resistance, IR), which proceeds toβ cell dysfunction. This present study assessed the modulatory effects of Buchholzia coriacea (B. coriacea) seeds extract in high fructose fed, streptozotocin induced T2D in male Wistar rats. Methanolic extract (MEBC), hexane fraction (HFBC), ethyl acetate fra... Continue Reading »

Item Type & Format: Project Material - Ms Word |  116 pages |  Instant Download  |  Chapter 1-5  |  BIOCHEMISTRY DEPARTMENT

10 P923497
EVALUATION OF NUTRITIVE AND NON-NUTRITIVE COMPONENTS AND ANTI-DIABETIC PROPERTIES OF EDIBLE PORTIONS OF CHRYSOPHYLLUM ALBIDUM FRUIT IN STREPTOZOTOCIN-...
CHAPTER ONE INTRODUCTION 1.1 Background to the Study Dietary control is vital in the management of diabetes. Reports from FAO (1998); WHO and FAO (2003) have shown that diets with low saturated fat, cholesterol and glycemic index as well as high contents of soluble fiber, vitamins and minerals are effective in the management of diabetes. Low glycemic foods contain sugars that digest and absorbed s... Continue Reading »

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11 P538797
PHYTOCHEMICAL ANALYSIS OF SELECTED TOMATO PRODUCTS
CHAPTER ONE 1.0 INTRODUCTION Intake of tomato and tomato based products contributes to the absorption of a wide range of carotenoids in human serum and tissues. The prominent carotenoid in tomatoes is lycopene, a pigment principally responsible for the deep red colour of tomato fruits and tomato products. Fruits and vegetables contain in excess of 40 carotenoids that are routinely absorbed and met... Continue Reading »

Item Type & Format: Project Material - Ms Word |  74 pages |  Instant Download  |  Chapter 1-5  |  BIOCHEMISTRY DEPARTMENT

12 P735976
INVESTIGATION OF THE PANCREATIC EFFECT OF BUCCHOLZIA CORICACEA FORMULATED DIET IN SUCROSE FED PREGNANT RATS AND THEIR OFFSPRING
ABSTRACT Several plants have been used in the treatment of various disorders without scientific basis. The present study examine the pancreatic effect of Buchholzia coriacea formulated diet in sucrose fed pregnant rats and their offspring. Buchholzia coriacea seeds were obtained from Ogbete main market, Enugu state, identified, dried and grounded using a miller machine. 10% of the seed powder was ... Continue Reading »

Item Type & Format: Project Material - Ms Word |  52 pages |  Instant Download  |  Chapter 1-5  |  BIOCHEMISTRY DEPARTMENT

13 P257143
EFFECTS OF ETHANOL, METHANOL AND N-HEXANE LEAF AND FRUIT EXTRACTS OF KIGELIA AFRICANA ON SOME OXIDATIVE AND BIOCHEMICAL PARAMETERS IN ALLOXAN-INDUCED ...
ABSTRACT Globally, the estimated incidence of diabetes and projection for the year 2030 as given by the International Diabetes Federation (IDF) is 350 million. Kigelia africana is highly used for ethno medicinal purposes although there is paucity of scientific information on its use. This work was therefore, aimed at evaluating the anti diabetic and antioxidative potential of the plant. Ethanol, m... Continue Reading »

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14 P385661
COMPARATIVE STUDY OF THE ADSORPTION CAPACITIES OF CHEMICALLY AND MICROWAVE SYNTHESIZED ACTIVATED CARBON
CHAPTER ONE INTRODUCTION 1.1 BACKGROUND OF STUDY Activated carbon, also widely known as activated charcoal or activated coal is a form of carbon which has been processed to make it extremely porous and thus to have a very large surface area available for adsorption or chemical reactions (Mattson et al., 1971). The word active is sometimes used in place of activated. It is characterized by high deg... Continue Reading »

Item Type & Format: Project Material - Ms Word |  52 pages |  Instant Download  |  Chapter 1-5  |  BIOCHEMISTRY DEPARTMENT

15 P217189
COMPARATIVE STUDY OF THE EFFECT OF RAUWOLFIA VOMITORIA ROOT-BARK EXTRACT ON SEX HORMONES IN MALE AND FEMALEALBINO WISTAR RATS
CHAPTER ONE INTRODUCTION 1.1 BACKGROUND OF STUDY Plants have been considered as sources of medicinal agents, as it offers natural products useful for human health. Since the existence of human life on the planet earth, plants have been the source of food, clothing, shelter, fiber, fuel and medicine. Since time immemorial plants are the principle raw materials of traditional medicinal system that h... Continue Reading »

Item Type & Format: Project Material - Ms Word |  60 pages |  Instant Download  |  Chapter 1-5  |  BIOCHEMISTRY DEPARTMENT

16 P130264
GARCINIA KOLA HECKEL STEM BARK ETHANOLIC EXTRACT AND ITS TRITERPENOID FRACTION PROTECTED AGAINST SODIUM ARSENITE-INDUCED HEPATOTOXICITY AND NEPHROTOXI...
... Continue Reading »

Item Type & Format: Project Material - Ms Word |  154 pages |  Instant Download  |  Chapter 1-5  |  BIOCHEMISTRY DEPARTMENT

17 P922878
ANGIOTENSIN CONVERTING ENZYME INHIBITORY ACTIVITY AND ANTIOXIDANT ACTIVITIES OF AQUEOUS EXTRACT OF COMBRETUM MICRANTHUM LEAVES
ABSTRACT Angiotensin I Converting Enzyme (ACE) is a glycoprotein with peptidyl dipeptide hydrolase activity which cleaves Angiotensin I to produce Angiotensin II. Angiotensin II is a powerful vasoconstrictor that as well regulates the synthesis of aldosterone that consequently interferes with blood pressure regulation. This study evaluates the effect of aqueous extract of Combretummicranthum leave... Continue Reading »

Item Type & Format: Project Material - Ms Word |  68 pages |  Instant Download  |  Chapter 1-5  |  BIOCHEMISTRY DEPARTMENT

18 P421328
COMBINED EFFECT OF ETHANOLIC EXTRACT OF GONGRONEMA LATIFOLIUM AND ALLIUM SATIVUM ON LIPID PROLIFE PARAMETERS ON STREPTOZOTOCIN INDUCED DIABETIC WISTAR...
TABLE OF CONTENT Title page i Cover page ii Certification iii Dedication iv Acknowledgment v Abstract vi Table of content vii CHAPTER ONE: INTRODUCTION 1.1 Background of the Study 1 1.2 Statement of the problem 3 1.3 Aim/Objectives of the Study 5 1.4 Justification of the Study 6 CHAPTER TWO: LITERATURE OF RELATED REVIEW 2.1 History of Diabetes 8 2.2 Classification of Diabetes 8 2.3 Medicinal Plant... Continue Reading »

Item Type & Format: Project Material - Ms Word |  60 pages |  Instant Download  |  Chapter 1-5  |  BIOCHEMISTRY DEPARTMENT

19 P957474
STUDY ON THE DESTABILIZATION OF LYSOZYME AND THE CHAPERONE-LIKE ACTIVITY OF ALPHA CRYSTALLIN FROM SOKOTO RED GOAT EYE LENS
ABSTRACT Destabilization of Lysozyme and chaperone like action of alpha crystallin isolated from goat’s eye lens was investigated at various temperature ranges in phosphate buffer (pH 7.1) solution and dithiothretol (DTT). This was monitored spectrophotometrically at 260nm. The heat and DTT induced destabilization of lysozyme was prevented by alpha crystallin in a concentration dependent manner.... Continue Reading »

Item Type & Format: Project Material - Ms Word |  52 pages |  Instant Download  |  Chapter 1-5  |  BIOCHEMISTRY DEPARTMENT

20 P652563
AN ASSESSMENT OF TEENAGE AWARENESS ON DIABETES MELLITUS FOR BEHAVIOUR CHANGE IN SELECTED SECONDARY SCHOOLS IN SABON GARI LGA OF KADUNA STATE
ABSTRACT In Nigeria, little attention has been paid to communicate and create awareness to teenagers about diabetes mellitus. Diabetes mellitus is a non communicable disease which has become aserious health challenge globally affecting both the young and old. This study examined how effective communication can deepen teenagers‟ knowledge on diabetes mellitus menace with a view to effecting posit... Continue Reading »

Item Type & Format: Project Material - Ms Word |  52 pages |  Instant Download  |  Chapter 1-5  |  BIOCHEMISTRY DEPARTMENT

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