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ABSTRACT
There is high risk of contracting hepatitis B and C among individuals with psychotic disorders due to lifestyle factors and prisoners globally continue to demonstrate a higher prevalence of Hepatitis B and C than the general population. This study was aimed at determining the seroprevalence of HCV and HBV and to detect hepatitis C virus (HCV) among prison inmates and psychiatric patients in Kaduna Metropolis. A total of 276 (153 prison inmates and 123 psychiatric patients) serum samples were tested for anti-HCV and Hepatitis B surface antigen (HBsAg) using third generation Enzyme Linked Immunosorbent Assay (ELISA) and RDT method respectively. Hepatitis C virus genome was detected in ten (10) serum samples using reverse transcription polymerase chain reaction (RT-PCR). An overall anti-HCV IgM prevalence of 10.14% (28/276), anti- HCV IgG prevalence of 8.69% (24/276) and HBsAg prevalence of 6.15% (17/276) was established. A 0.36% (1/276) HCV/HBV co-infection rate was obtained. Among the inmates, an anti-HCV IgM and IgG prevalence of 10.45% (16/153) and 8.5% (13/153) respectively was obtained with a 9.2% (14/153) HBsAg prevalence. An HBsAg, anti-HCV IgM and anti-HCV IgG prevalence of 2.4% (3/123), 9.75% (12/123) and 8.9% (11/123) respectively was obtained among the psychiatric patients. The highest HCV antibody prevalence was obtained among the female subjects (14.1% for IgM and 8.4% for IgG). No female tested positive for HBsAg. Subjects aged ≥48 years had the highest HCV prevalence (28.9%: 13/45 for IgM and 31.1%: 14/45 for IgG) while those within age group 28-32 years had the highest HBsAg prevalence (11.7%: 7/60). Age was observed to be associated with HCV infection (p=0.00). Viremia was evaluated by amplifying conserved untranslated region of HCV genome and bands of 244bp were observed. There was no statistically significant association between the viral infections and demographics. Presence of tattoo/scarification and alcohol intake were statistically associated with HCV infection while clothes sharing was associated with HBsAg among the inmates. Hepatitis C virus infection was statistically associated with blood transfusion, alcohol intake, presen
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SIMILAR MICROBIOLOGY FINAL YEAR PROJECT RESEARCH TOPICS
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1. BACTERIOLOGICAL STUDY OF SACHET WATER SOLD IN OWERRI METROPOLIS
» ABSTRACT Water is one of the indispensable resources for the continued existence of all living things including man. The provision of an adequate supp...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages |
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2. MICROBIOLOGICAL ASSESSMENT OF INDOORANDOUTDOORAIROF FAITH MEDIPLEX HOSPITAL, BENIN CITY
» ABSTRACT This study was aimed at investigating the microbial load and the quality of indoor air Faith Mediplex Centre, Benin City, to ascertain their ...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages |
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3. BACTERIOLOGICAL AND PHYSICOCHEMICAL QUALITY ASSESSMENT OF PACKAGED AND OTHER DRINKING WATER SOURCES IN ZARIA, KADUNA STATE, NIGERIA
» ABSTRACT Continuous increase in the sale and indiscriminate consumption of packaged drinking water and untreated water types such as borehole and well...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages |
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4. MICROBIAL EXAMINATION OF SPOILT AVOCADO FRUIT
» ABSTRACT Microbial examination of spoilt Avocado fruits was carried out to obtained the causal organism. A total of 60 avocado from Ogbete Main market...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages |
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5. DETECTION OF HEPATITIS C AND HEPATITIS B VIRUS INFECTION AMONG PRISON INMATES AND PYCHIATRIC PATIENTS IN KADUNA METROPOLIS, NIGERIA
» CHAPTER ONE 1.0 INTRODUCTION Hepatitis C virus (HCV) is a small enveloped virus measuring 55 65nm in size. It is a positive sense single stranded RNA ...Continue Reading »Item Type & Format: Project Material - Ms Word | 102 pages |
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6. ISOLATION AND IDENTIFICATION OF BACTERIA FROM FOOD VENDORS AND SOME VEGETABLE AVAILABLE AT OGBETE MARKET ENUGU.
» ABSTRACT Safety of food is a basic requirement of food quality. A total of 25 street food samples (Jollof rice, egwusi soup, ugu, water leaf and green...Continue Reading »Item Type & Format: Project Material - Ms Word | 66 pages |
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7. ISOLATION AND IDENTIFICATION OF MICROORGANISM IN STREAM WATER [ATOLAGBE] IREE TOWN
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8. ANTIBACTERIAL ACTIVITIES OF Carica papaya SEED AGAINST ENTERIC ORGANISMS
» ABSTRACT Lots of research has been conducted on Carica papaya and its antibacterial efficacy on bacterial pathogens and this led to this study on anti...Continue Reading »Item Type & Format: Project Material - Ms Word | 37 pages |
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9. ANALYSIS OF BUSH PEAR AND ITS OIL
» ABSTRACT The research project studies the analysis of pear and its oil. The mesocarp from edible African pear “DacryodesEdulis” were evalu...Continue Reading »Item Type & Format: Project Material - Ms Word | 91 pages |
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10. COMPARATIVE STUDY OF DISINFECTANT EFFICIENCY OF ETHANOL, BLEACH AND PHENOLICS AGAINST Pseudomonas aeruginosa and Staphylococcus aureus
» ABSTRACTEthanol, Bleach and Phenolics are three kinds of disinfectants which have been widely used in common laboratories. In this study, a compared e...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages |
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