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ABSTRACT
There is high risk of contracting hepatitis B and C among individuals with psychotic disorders due to lifestyle factors and prisoners globally continue to demonstrate a higher prevalence of Hepatitis B and C than the general population. This study was aimed at determining the seroprevalence of HCV and HBV and to detect hepatitis C virus (HCV) among prison inmates and psychiatric patients in Kaduna Metropolis. A total of 276 (153 prison inmates and 123 psychiatric patients) serum samples were tested for anti-HCV and Hepatitis B surface antigen (HBsAg) using third generation Enzyme Linked Immunosorbent Assay (ELISA) and RDT method respectively. Hepatitis C virus genome was detected in ten (10) serum samples using reverse transcription polymerase chain reaction (RT-PCR). An overall anti-HCV IgM prevalence of 10.14% (28/276), anti- HCV IgG prevalence of 8.69% (24/276) and HBsAg prevalence of 6.15% (17/276) was established. A 0.36% (1/276) HCV/HBV co-infection rate was obtained. Among the inmates, an anti-HCV IgM and IgG prevalence of 10.45% (16/153) and 8.5% (13/153) respectively was obtained with a 9.2% (14/153) HBsAg prevalence. An HBsAg, anti-HCV IgM and anti-HCV IgG prevalence of 2.4% (3/123), 9.75% (12/123) and 8.9% (11/123) respectively was obtained among the psychiatric patients. The highest HCV antibody prevalence was obtained among the female subjects (14.1% for IgM and 8.4% for IgG). No female tested positive for HBsAg. Subjects aged ≥48 years had the highest HCV prevalence (28.9%: 13/45 for IgM and 31.1%: 14/45 for IgG) while those within age group 28-32 years had the highest HBsAg prevalence (11.7%: 7/60). Age was observed to be associated with HCV infection (p=0.00). Viremia was evaluated by amplifying conserved untranslated region of HCV genome and bands of 244bp were observed. There was no statistically significant association between the viral infections and demographics. Presence of tattoo/scarification and alcohol intake were statistically associated with HCV infection while clothes sharing was associated with HBsAg among the inmates. Hepatitis C virus infection was statistically associated with blood transfusion, alcohol intake, presen
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SIMILAR MICROBIOLOGY FINAL YEAR PROJECT RESEARCH TOPICS
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1. CHLAMYDIA INFECTIONS, HOW TO CONTROL & ERADICATE IT
» CHAPTER ONE INTRODUCTION Chlamydiae are small gram negative obligate intracellular microorganisms that preferentially infect squamocolumnar epithelial...Continue Reading »Item Type & Format: Project Material - Ms Word | 43 pages |
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2. COMPARATIVE STUDY OF GLUTAMIC ACID PRODUCTION BY WILD-TYPE AND MUTANT STRAINS OF CORYNEBACTERIUM GLUTAMICUM
» ABSTRACT Several different lignocellulosic biomass of agricultural origin hold remarkable potential for conversion into commodity products presenting ...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages |
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3. AVAILABILITY OF LABORATORY FACILITIES FOR EFFECTIVE TEACHING AND LEARNING OF SHIP BUILDING IN MARITIME ACADEMY OF NIGERIA
» CHAPTER ONE INTRODUCTION 1.1 Background of the Study Education, according to Coombs (1970) consists of two components. He classified these two compone...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages |
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4. PHYTOCHEMICAL AND ANTIMICROBIAL ANALYSIS OF MYSTLETOE LEAVES
» CHAPTER ONE 1.0 INTRODUCTION The use of the leaves, stem and bark of the plants for medicinal purposes is an age long practice. Also in the modern tim...Continue Reading »Item Type & Format: Project Material - Ms Word | 55 pages |
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5. ANTIBACTERIAL ACTIVITIES OF Carica papaya SEED AGAINST ENTERIC ORGANISMS
» ABSTRACT Lots of research has been conducted on Carica papaya and its antibacterial efficacy on bacterial pathogens and this led to this study on anti...Continue Reading »Item Type & Format: Project Material - Ms Word | 37 pages |
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6. ASSESSMENT OF NEWCASTLE DISEASE VIRUS ANTIBODIES AMONG BIRDS REARED
» CHAPTER ONE1.0 INTRODUCTIONNewcastle disease (ND) is one of the most important avian viral diseases because of its high economic impact on the poultry...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages |
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7. ISOLATION AND IDENTIFICATION OF AIR MICROFLORA IN MICROBIOLOGY LABORATORY
» ABSTRACT Microflora contamination in laboratories and hospitals is becoming a serious problem worldwide, and the characterization of such contaminants...Continue Reading »Item Type & Format: Project Material - Ms Word | 62 pages |
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8. A SURVEY OF THE ANTIBACTERIAL ACTIVITY OF THYMUS VULGARIS AND MYRISTICA FRAGRANS ON STREPTOCOCUSS PNEUMONIAE AND PSEUDOMONAS AERUGINOSA
» ABSTRACT The aqueous and ethanolic extracts of the leaves of Thymus vulgaris (thyme) and the seeds of Myristica fragrans (nutmeg) were screened for th...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages |
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9. ASSESSMENT OF EXTRACELLULAR BETA-GALACTOSIDASE PRODUCTION POTENTIAL OF FUNGI ISOLATED FROM DAIRY EFFLUENT
» ABSTRACT Dairy wastewater is increasingly becoming an environmental concern. There is a widespread interest in the use of beta galactosidase (EC 3.2.1...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages |
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10. A COMPARATIVE INVESTIGATION INTO THE LIPID PROFILE OF MORINGA OLEIFERA SEEDS AND LEAVES
» ABSTRACT Moringa Oleifera seed and leaves and other parts of the plants used in Eastern Nigeria have an impressive range of multipurpose medicinal use...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages |
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