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ABSTRACT
There is high risk of contracting hepatitis B and C among individuals with psychotic disorders due to lifestyle factors and prisoners globally continue to demonstrate a higher prevalence of Hepatitis B and C than the general population. This study was aimed at determining the seroprevalence of HCV and HBV and to detect hepatitis C virus (HCV) among prison inmates and psychiatric patients in Kaduna Metropolis. A total of 276 (153 prison inmates and 123 psychiatric patients) serum samples were tested for anti-HCV and Hepatitis B surface antigen (HBsAg) using third generation Enzyme Linked Immunosorbent Assay (ELISA) and RDT method respectively. Hepatitis C virus genome was detected in ten (10) serum samples using reverse transcription polymerase chain reaction (RT-PCR). An overall anti-HCV IgM prevalence of 10.14% (28/276), anti- HCV IgG prevalence of 8.69% (24/276) and HBsAg prevalence of 6.15% (17/276) was established. A 0.36% (1/276) HCV/HBV co-infection rate was obtained. Among the inmates, an anti-HCV IgM and IgG prevalence of 10.45% (16/153) and 8.5% (13/153) respectively was obtained with a 9.2% (14/153) HBsAg prevalence. An HBsAg, anti-HCV IgM and anti-HCV IgG prevalence of 2.4% (3/123), 9.75% (12/123) and 8.9% (11/123) respectively was obtained among the psychiatric patients. The highest HCV antibody prevalence was obtained among the female subjects (14.1% for IgM and 8.4% for IgG). No female tested positive for HBsAg. Subjects aged ≥48 years had the highest HCV prevalence (28.9%: 13/45 for IgM and 31.1%: 14/45 for IgG) while those within age group 28-32 years had the highest HBsAg prevalence (11.7%: 7/60). Age was observed to be associated with HCV infection (p=0.00). Viremia was evaluated by amplifying conserved untranslated region of HCV genome and bands of 244bp were observed. There was no statistically significant association between the viral infections and demographics. Presence of tattoo/scarification and alcohol intake were statistically associated with HCV infection while clothes sharing was associated with HBsAg among the inmates. Hepatitis C virus infection was statistically associated with blood transfusion, alcohol intake, presen
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SIMILAR MICROBIOLOGY FINAL YEAR PROJECT RESEARCH TOPICS
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1. A PRACTICAL CARRIED OUT AT X-RAY DEPARTMENT, SHEHU MUHAMMAD KANGIWA MEDICAL CENTRE (S.M.K.M.C), KADUNA POLYTECHNIC, KADUNA STATE
» ABSTRACT Diagnostic x ray is useful in detecting abnormalities within the body. They are a painless, non invasive way to help diagnose problems such a...Continue Reading »Item Type & Format: Project Material - Ms Word | 21 pages |
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2. THE ISOLATION AND IDENTIFICATION OF NEMATODE AFFECTING TOMATOES
» CHAPTER ONE 1.0 INTRODUCTION: Nematodes are tiny, thread like worms measuring 0.0 15 inch to 0.187 inch in length. They are either free living parasit...Continue Reading »Item Type & Format: Project Material - Ms Word | 34 pages |
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3. ISOLATION AND IDENTIFICATION OF MICROORGANISM IN STREAM WATER [ATOLAGBE] IREE TOWN
» ABSTRACT The stream water was examined for microorganism present in it. The isolated and identified bacteria are Bacillus cereus and Staphylococcus au...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages |
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4. BIOCONTROL POTENTIAL OF BACILLUS THURINGIENSIS ISOLATED FROM SOIL SAMPLES AGAINST LARVA OF MOSQUITO
» ABSTRACT A major challenge for achieving successful mosquito control is overcoming insecticide resistance. Bacillus thuringiensis which is one of the ...Continue Reading »Item Type & Format: Project Material - Ms Word | 49 pages |
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5. COMPARATIVE ANALYSIS OF PIPEBORNE WATER AND OTHER SOURCES OF WATER WITHIN ENUGU METROPOLIS FOR HUMAN CONSUMPTION.(INDEPENDENCE LAYOUT LOCALITY)
» ABSTRACT Comparative examination of three main sources of water supply in Independence layout Enugu was carried out with a view to determine their lev...Continue Reading »Item Type & Format: Project Material - Ms Word | 44 pages |
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6. DETECTION OF SCHISTOSOMASPECIES IN CENTRAL RIVER REGION OF THE GAMBIA
» ABSTRACT A study on schistosomiasis infection was carried out among students, farmers and fishers (fishermen/women) from four villages in the Central ...Continue Reading »Item Type & Format: Project Material - Ms Word | 100 pages |
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7. MICROBIAL PROFILE OF SUYA MEAT IN ENUGU STATE
» CHAPTER ONE 1.0 INTRODUCTION 1.1 BACKGRONUD OF THE STUDY Meat is the flesh of animals which serves as food; it is obtained from sheep, cattle, goat an...Continue Reading »Item Type & Format: Project Material - Ms Word | 57 pages |
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8. PRELIMINARY PHYTOCHEMICAL AND ANTIMICROBIAL SCREENING OF SEED AND COAT OF Citrus sinensis
» CHAPTER ONE INTRODUCTION The Citrus sinensis popularly known as sweet orange seed in Igbo of Nigeria is of the Rutaceae family. The seed is best sown ...Continue Reading »Item Type & Format: Project Material - Ms Word | 44 pages |
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9. CHARACTERIZATION OF SALMONELLA SPECIES AND DETERMINATION OF BASELINE ANTIBODY TITRE AMONG APPARENTLY HEALTHY INDIVIDUALS IN KADUNA STATE, NIGERIA
» ABSTRACT This study was conducted to determine the baseline antibody titre, isolate and characterize Salmonella species from apparently healthy indivi...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages |
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10. A COMPARATIVE INVESTIGATION INTO THE LIPID PROFILE OF MORINGA OLEIFERA SEEDS AND LEAVES
» ABSTRACT Moringa Oleifera seed and leaves and other parts of the plants used in Eastern Nigeria have an impressive range of multipurpose medicinal use...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages |
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