- The Complete Research Material is averagely 60 pages long and it is in Ms Word Format, it has 1-5 Chapters.
- Major Attributes are Abstract, All Chapters, Figures, Appendix, References.
- Study Level: BTech, BSc, BEng, BA, HND, ND or NCE.
- Full Access Fee: ₦6,000
Get the complete project »
![Download Code Ready Instant Download Active](https://codemint.net/assets/home/instantdownloadMain.png)
CHAPTER ONE
INTRODUCTION
1.1 BACKGROUND OF STUDY
Plants have been considered as sources of medicinal agents, as it offers natural products useful for human health. Since the existence of human life on the planet earth, plants have been the source of food, clothing, shelter, fiber, fuel and medicine. Since time immemorial plants are the principle raw materials of traditional medicinal system that has been practiced and continue to provide mankind with novel therapies (Cragg and Newmann, 2005). Rauwolfia vomitoria , is a plant specie that of the genus Rauvolfia. It is also called the "poison devils pepper". Rauwolfia vomitoria contains a large number of indole alkaloids, the root bark contains reserpiline as a major component, followed by reserpine, reserpinine and ajmaline. Root products of Rauwolfia vomitoria have been found to be potent in treatment hypertension, as a sedative to calm epilepsy and psychotic or mental illness. They are also used to wash Children with Colic or fever as well as for skin problems such as rash, pimples, etc. (Schmelzer, 2007).
Sex hormones are natural substances produced by the body that helps relay messages between cells and organs and affect development of sexual organs and other secondary sexual characteristics. Estrogen and progesterone are the two main female sex hormones. Although testosterone is considered as a male hormones females also produce and use a small amount of it too.
Estrogen is the major female hormones. The major amount of the estrogen is produced by the ovaries but small amounts are produced in the adrenal glands and fat cells. During pregnancy, the placenta also makes estrogen. Estrogen plays a big role in reproduction and sexual development, including puberty, menstruation, pregnancy and menopause.
The ovaries also produces the progesterone after ovulation and during pregnancy, the placenta also produces some. Progesterone plays a role in preparing the lining of the uterus for a fertilized egg, supporting pregnancy and suppressing of estrogen production after ovulation.
Testosterone is a male sex hormone that is important for sexual and reproductive development. It is responsible for development of male sex organs before birth as well as development of other secondary characteristics.
1.2 STATEMENT OF THE PROBLEM
Alkaloids have been reported to show varying effects on the serum hormone levels. Rauwolfia vomitoria has a vast composition of alkaloids and is potent in treatment and management of various ailments. However, there is not enough information as to the effect of Rauwolfia vomitoria root bark extract on the levels of sex hormones.
1.3 AIM AND OBJECTIVES OF THE STUDY
The aim of the study is to evaluate the effect of Rauwolfia vomitoria root bark extract on male and female sex hormones.
1.4 SIGNIFICANCE OF THE STUDY
The result from this study will add more knowledge to our existing biomedical and pharmacological potentials of Rauwolfia vomitoria and this may help open up new avenues of investigation for researchers.
1.5 JUSTIFICATION OF THE STUDY
Medicinal plants have received a great deal of attention due to their possible beneficial as well as adverse effects. Some of these plants are known to possess anti- fertility effect through their action on hypothlamo-pituitary-gonadal axis or direct hormonal effects on reproductive organs resulting in inhibition of ovarian steroidogenesis. Sex hormones are natural substances produced by the body that helps relay messages between cells and organs and affect development of sexual organs and other secondary sexual characteristics. Alteration in the levels of these sex hormones may lead to infertilty, abortion, abnormal development of sexual characteristics and sexual organs in male, hence the need for use of medicinal plants as a means of regulating hormonal levels by way of increasing or decreasing it.
1.6 SCOPE OF THE STUDY
The scope of the study includes:
i. Administration of ethanol extract of Rauwolfia vomitoria to male and female albino Wistar rats depending on body weight
ii. Collection of blood by cardiac puncture from anaesthetized experimental rats
iii. Separation of serum by centrifugation
iv. Determination of biochemical parameters
You either get what you want or your money back. T&C Apply
![](https://codemint.net/assets/public/img/100-money-back-guarantee.png)
You can find more project topics easily, just search
-
SIMILAR BIOCHEMISTRY FINAL YEAR PROJECT RESEARCH TOPICS
-
1. TRACE ELEMENTS CONTENT OF NEEM LEAVES (AZADIRACHTA INDICA).
» CHAPTER ONE 1.0 INTRODUCTION Neem (Azadirachta indica A. Juss) is one of the very few trees known in the Indian subcontinent (Puri, 1999). This tree b...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages |
Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
2. EFFECT OF PROCESSING (TOASTING AND FERMENTATION) ON THE NUTRITIONAL VALUE OF SICKLE POD (Senna obtusifolia) SEEDS
» ABSTRACT The effects of fermentation and toasting on the nutrients and antinutrients composition of Senna obtusifoliai seeds were investigated. Senna ...Continue Reading »Item Type & Format: Project Material - Ms Word | 112 pages |
Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
3. ASSESSMENT OF THE RELATIONSHIP BETWEEN FOETAL HAEMOGLOBIN LEVELS, MARKERS OF TISSUE DESTRUCTION AND DISEASE SEVERITY IN INDIVIDUALS WITH SICKLE CELL ...
» ABSTRACT Sickle cell Anaemia is a genetic disorder that leads to the production of Sickle haemoglobin, whichresults in abnormal functions of the red b...Continue Reading »Item Type & Format: Project Material - Ms Word | 72 pages |
Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
4. EVALUATION OF ANTIOXIDANT POTENTIAL OF MONODORA MYRISTICA (AFRICAN NUTMEG)
» ABSTRACT This work evaluates the antioxidant potential of Monodora myristica (African nutmeg). Monodora myristica extract was obtained by solvent extr...Continue Reading »Item Type & Format: Project Material - Ms Word | 76 pages |
Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
5. EFFECTS OF KOLAVIRON ON LYMPHOCYTES PROLIFERATION, EXPRESSION OF TOLL LIKE RECEPTOR-2 AND VASCULAR ENDOTHELIAL GROWTH FACTOR-C GENES IN Wuchereria ban...
» ABSTRACT The anti proliferative effect and down regulation of vascular endothelial growth factor C and toll like receptor 2 by kolaviron rich portion ...Continue Reading »Item Type & Format: Project Material - Ms Word | 72 pages |
Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
6. DETERMINATION OF ACTIVE SWEET COMPONENTS OF COMMON ARTIFICIAL SWEETENERS THAT ARE USED AS REPLACEMENT FOR SUGAR
» CHAPTER FIVE DISCUSSION AND CONCLUSION Discussion: Table 1 shows the taste with distilled waterused as control. In Table 2, there is a change in the t...Continue Reading »Item Type & Format: Project Material - Ms Word | 50 pages |
Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
7. THE EVALUATION OF MICROORGANISMS ON GARRI AT OGBETE MARKET
» ABSTRACT The research focus on compensation policy as means of attracting and retaining employee, it present a conceptual and theoretical study of the...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages |
Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
8. UREA AND CREATININE CONCENTRATIONS OF PLASMODIUM BERGHEI INFECTED MICE TREATED WITH COARTEM, HIPPROCRATEA AFRICANA ROOT BARK EXTRACT, CIPROFLOXACIN AN...
» ABSTRACT The concomitant effect of Hippocratea africana root bark extract, Jatropha tanjorensis Ciprofloxacin and Coartem on markers (Urea and Creatin...Continue Reading »Item Type & Format: Project Material - Ms Word | 57 pages |
Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
9. SCREENING SOME MEDICINAL PLANTS AGAINST MOROCCAN WATERMELON MOSAIC VIRUS (MWMV)
» ABSTRACT The antiviral activities of plant leaves extract of four species, were investigated. The extract were tested for antiviral activities on the ...Continue Reading »Item Type & Format: Project Material - Ms Word | 50 pages |
Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
10. EVALUATION OF THE ANTIDIABETIC EFFECTS OF WATER AND METHANOLIC EXTRACTS OF AVOCADO (PERSEA AMERICANA) SEED ON ALLOXAN INDUCED DIABETIC RATS
» ABSTRACT The high prevalence, complications and cost of conventional drugs in the management diabetes necessitated the search for alternative treatmen...Continue Reading »Item Type & Format: Project Material - Ms Word | 50 pages |
Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT