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ABSTRACT
Fusarium oxysporum is an important pathogen of a wide range of
crop plants. The study was conducted to investigate the effect of
feeding a blend of sorghum grains contaminated with Fusarium
oxysporum on the blood picture and the histology of the kidney and
liver of adult wistar rats. A total of thirty (30) rats of the wistar
7
species weighing between 150 and 180g were divided into four
experimental groups and a control group comprising six(6) rats in
each group and fed for twenty eight days(28).The diet consisted
control(group 1),25% contaminated meal(group 2),50%
contaminated(group 3),75% contaminated(group 4) and 100%
contaminated meals(group 5).
At the end of the experiment the RBC, WBC and differential
WBC counts did not show any significant differences (P 0.05).the
histological studies however showed damage to the kidney tissue
under light microscopy. They were characterized by degraded renal
tubules, necrosis of glomerular cells, and apoptotic bodies in areas
between the renal tubules infiltrated by mononuclear cells.
The liver histology showed by light microscopy, loss of hepatic
architecture, pyknotic nuclei and infiltration by mononuclear cells.
It was therefore concluded that Fusarium oxysporum has caused
marked inflammation and tubular necrosis in the rat’s kidney as
well as inflammation and parenchymal necrosis in the liver with no
significant changes in the blood picture.
CHAPTER ONE
1.1
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SIMILAR ANATOMY FINAL YEAR PROJECT RESEARCH TOPICS
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2. DRUGS /SUBSTANCES ABUSE AMONG STUDENTS OF KADUNA POLYTECHNIC
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3. THE EFFECT OF QUININE AND TRIPLE ANTIRETROVIRAL REGIMEN ON THE HISTOLOGY OF THE FETAL CEREBELLUM OF ALBINO WISTAR RATS
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5. EFFECT OF ORAL ADMINISTRATION OF ALUMINIUM CHLORIDE ON THE HIPPOCAMPUS (BRAIN) OF WISTAR RATS
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6. ASSESSMENT OF PLANTAR ARCH INDEX AND PREVALENCE OF FLAT FEET AMONG RESIDENTS IN OVIA NORTHEAST L.G.A, EDO STATE
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8. ANTHROPOMETRIC COMPARISM OF CEPHALIC INDICES BETWEEN YORUBA AND BENIN ETHNIC GROUPS RESIDING IN OKADA TOWN, EDO STATE.
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9. Anthropometric Study and Stature Estimation in Lokaa, Ayiga, Agoi and Ekoi Ethnic Groups of Yakurr Local Government Area of Cross River State, Nigeria
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10. THE EFFECT OF ORAL ADMINISRATION OF Pausinystalia yohimbe ON THE HAEMATOLOGICAL PARAMETERS AND HISTOLOGY OF THE HYPOTHALAMUS OF ADULT MALE WISTAR RATS
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