Get the complete project »
- The Complete Research Material is averagely 52 pages long and it is in Ms Word Format, it has 1-5 Chapters.
- Major Attributes are Abstract, All Chapters, Figures, Appendix, References.
- Study Level: BTech, BSc, BEng, BA, HND, ND or NCE.
- Full Access Fee: ₦4,000
Toward the end of the 20th century, epidemiological studies and associated meta-analyses suggested strongly that long-term consumption of diets rich in plant foods offered some protection against chronic diseases, especially cancer (Wallstromet al., 2000).Because uncontrolled production of free radicals was thought to be significantly implicated in the etiology of cancer (Guyton and Kensler 1993),these observations focused attention on the possible role of radical scavenging and radical suppressing nutrients and non-nutrients in explaining the apparent benefit of such diets (Weisburger, 1991).
The realization that free radicals were similarly implicated in the etiology of many other chronic diseases (Kehrer, 1993 and Stohs, 1995), immediately focused attention on flavonoids and the foods and beverages rich therein. An unfortunate, but unintended side effect of some research works and papers was the misleading tendency of many investigators to think of dietary phenols, polyphenols, and tannins (PPT)as encompassing only the flavonoids, flavonols, and flavones. More recent epidemiological studies have supported the association between better health and long-term consumption of diets rich in foods of plant origin(Hung et al., 2004 and Jansen et al., 2004).However, whether this is because such diets minimize exposure to deleterious substances (example oxidized cholesterol, pyrolysis mutagens, salt, saturated fat, etc.), or maximize intake of certain beneficial nutrients (example isothiocyanates and other sulfur-containing plant constituents, mono-unsaturated fatty
acids, and poly-unsaturated fatty acids, PPT, polyacetylenes, selenium, terpenes, etc.) or some combination as advocated in the ‘‘Polymeal’’ concept, remains unknown (Franco et al., 2004 and Johnson, 2004).An in vitro study indicates that there may be mechanistic basis for true synergy between PPT and isothiocyanates. In contrast, more recent studies seeking to assess the suggested link between the consumption of flavonols and flavones, or other flavonoids, have given much less consistent results. Some studies have suggested a possible protective effect of flavonoids against vascular diseases (Hirvonen et al., 2001 and Mennen et al., 2004) or certain (but not all) cancers(Knekt et al., 1997 and Sun et al., 2002).Interestingly, an investigation of the relationship between the consumption of Hibiscus sabdariffa (zobo) and other cruciferous vegetables and the risk of breast cancer in premenopausal women has to be carried out in order to ascertain the beneficial effects to isothiocyanates and/or the phenolic components of the plants (like the dietary phenols including flavonoids) in the management of cancer growth and initiation of various types of diabetes.
In the same time period, various studies have suggested beneficial effect associated with raised consumption of other classes of dietary phenols. For example, increased coffee consumption has been linked with reduced incidence of type II diabetes (van Dam et al., 2002 and Saremi et al., 2003).Similarly, increased consumption of lignans (or at least greater plasma concentrations of their metabolites)has been linked with reduced incidence of estrogen-related cancers in some (Boccardo et al., 2004 and McCann et al., 2004) but not all studies (Kilkkinen et al., 2004 and Zeleniuch –Jacquotte et al., 2004),and a prospective study was equivocal.
1.1 SUGGESTIONS FOR FURTHER RESEARCH
The flavonoids in the water extract of Hibiscus sabdariffa should be extracted for further experimental and clinical research in the management of certain ailments and disorders like cancer, diabetes mellitus etc.
The mechanisms of flavonoid-protein interactions have been determined; it is my suggestion that such mechanisms should be carried to the in-vivo metabolic and physiological processes aimed at determining the detailed mechanisms involved in cells aging processes and the progression of diseases.
1.2 OBJECTIVE OF STUDY
The objective of this study is to determine the physico chemical (biochemical) and water constituent of Zobo produced from dried calyces of Hibiscus sabdariffa (Linn Roselle). Using atomic absorption spectrophotometer (AAS). The biochemical content of the zobo has undesirable effects on human health when consumed.
You either get what you want or your money back. T&C Apply
You can find more project topics easily, just search
SIMILAR MICROBIOLOGY FINAL YEAR PROJECT RESEARCH TOPICS
1. HEPATITIS C VIRUS AMONG PREGNANT WOMENPEOPLE LIVING WITH HIVAIDS ATTENDING CLINIC AT UNTH ITUKUOZALLA» ABSTRACT A total of 50 blood (30 pregnant and 20 HIV) samples were obtained from pregnant women and PLWHA attending clinic at UNTH Ituku ozalla. Sampl...Continue Reading »
» CHAPTER ONE 1.0 INTRODUCTION The use of the leaves, stem and bark of the plants for medicinal purposes is an age long practice. Also in the modern tim...Continue Reading »
3. DESIGN AND IMPLEMENTATION OF AN EXPERT SYSTEM ON THYPHOID AND MALARIA DIAGNOSIS (A case study of Park Lane Hospital Enugu)» CHAPTER ONE INTRODUCTION 1.1 Background of the Study An expert system is a software system that attempts to reproduce the performance of one or more h...Continue Reading »
» ...Continue Reading »
5. BIOETHANOL PRODUCTION FROM SUGARCANE BAGASSE AND RICE STALK USING LOCAL STRAINS OF ASPERGILLUS NIGERANDSACCHAROMYCES CEREVISIAE AS CO-CULTURES» ABSTRACT This study was aimed at producing an alternative energy source(bioethanol)from sulphuric acid and alkaline hydrogen peroxide treated sugarcan...Continue Reading »
6. EFFECTS OF ETHANOL LEAVES EXTRACT OF Jatropha tanjorensis ON HAEMATOLOGICAL INDICES OF MALE ALBINO WISTAR RATS» ABSTRACT The study was carried out to determine the effects of ethanol leaves extract of Jatropha tanjorensis on haematological indices of mature albi...Continue Reading »
7. PHYTOCHEMICAL ANALYSIS AND ANTIMICROBIAL ACTIVITY OF Acalypha wilkesiana EXTRACT AGAINST CLINICAL ISOLATES OF Candida albicans» ABSTRACT The increased, sustained interest in the production of plant based drugs for the treatment of many diseases has become a significant reason w...Continue Reading »
» CHAPTER ONE 1.0 INTRODUCTION Ugba also called ukpaka is a popular food delicacy in Nigeria especially among Ibo ethnic group. It is rich in protein an...Continue Reading »
9. ANTIBACTERIAL ACTIVITY OF HONEY ON Staphylococcus aureusEscherichia coli and Streptococcus pyogen ISOLATED FROM WOUND» ABSTRACT Antibacterial activity of honey obtained from two different locations in Enugu State (Nsukka & Ugwuaji) Nigeria on Staphylococcus aureus,...Continue Reading »
10. DETECTION OF HEPATITIS C AND HEPATITIS B VIRUS INFECTION AMONG PRISON INMATES AND PSYCHIATRIC PATIENTS IN KADUNA METROPOLIS, NIGERIA» ABSTRACT There is high risk of contracting hepatitis B and C among individuals with psychotic disorders due to lifestyle factors and prisoners globall...Continue Reading »