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CHAPTER ONE
INTRODUCTION
The term “lymphatic filariasis” covers infections with three closely related nematode
worms- wuchereria bancrofti, Brugia malayi and brugia timori. All three infections are
transmitted to man by the bite of an infected mosquito through the skin.1 These larvae
then migrate to the lymphatic vessels and develop into adult worms, over a period of six
to twelve months, causing damage and dilatation of the lymphatic vessels. The filariae
live for several years in the human host. During this period they produce millions of
immature microfilaria that circulate in the peripheral blood and are ingested by
mosquitoes when they bite infected humans. The larval forms further develop inside the
mosquitoes before becoming infectious to man. Thus a cycle of transmission is
established.2,3,4
Lymphatic Filariasis is a global Public Health problem with eighty-three countries
endemic for the disease. There are approximately 1.1 billion people at risk for contracting
lymphatic filariasis and 120 million people are infected world-wide. 5 The disease is the
second most common vector borne parasitic disease after malaria. It is also the second
most common cause of long term disability after mental illness. One third of infected
people live in India, one third in Africa, the remainder live in the Americas, the Pacific
Island, Papua New Guinea and S.E. Asia.6
Four countries- India, Indonesia, Nigeria and Bangladesh account for 70% of all
Lymphatic filariasis. infections. Nigeria is the third most endemic country in the world
for the disease, with an estimated 22 million cases. Estimates of annual economic loss in
India due to the disease approach 1 billion U.S. dollars; the economic impact in Nigeria is
unknown but expected to be significant.7
14
In communities where the disease is endemic as many as 10 percent of women can be
affected with swollen limbs and 50 percent of men can suffer from mutilating genital
symptoms.8 Filariae are responsible for a variety of clinical manifestations including
lymphoedema of the limbs, genital disease (hydrocele, chylocele and swelling of the
scrotum and penis) and acute recurrent secondary bacterial infections known as “acute
attacks”. The vast majority of infected are asymptomatic but virtually all of them have
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3. DETERMINANTS OF UTILIZATION OF FAMILY PLANNING SERVICES AMONG WOMEN OF CHILD-BEARING AGE IN RURAL AREAS OF KANO STATE, NORTHERN NIGERIA
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4. PREVALENCE OF HEPATITIS VIRUS INFECTION AMONG PREGNANT WOMEN
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6. PREVALENCE AND DETERMINANTS OF HIV RISK BEHAVIOURS AMONG SEAFARERS IN PORT HARCOURT SEAPORT RIVERS STATE
» SUMMARY HIV/AIDS in seafaring is a global health issue with adverse effects on the seafarers and the economy at large. In spite of the role of seafari...Continue Reading »Item Type & Format: Project Material - Ms Word | 97 pages |
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7. FACTORS INFLUENCING ADOLESCENTS’ SEXUALITY AND REPRODUCTIVE HEALTH SEEKING BEHAVIOUR IN IBADAN SOUTHEAST LOCAL GOVERNMENT AREA OF OYO STATE
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8. PREVALENCE AND DETERMINANTS OF HYPERTENSION AMONG CIVIL SERVANTS, IN KANO STATE, NIGERIA
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