EFFECT OF CAFFEINE ON BLOOD GLUCOSE AND LIPID PROFILE IN ALLOXAN-INDUCED DIABETIC WISTAR RATS

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Abstract

Diabetes mellitus is characterized by hyperglycemia. Caffeine has been suggested to be capable of disrupting glucose metabolism. The effects of caffeine on blood glucose level and on lipid profile of alloxan induced diabetic Wistar rats were studied. The effect of caffeine by determining the blood glucose levels at intervals of 30mins, 1hour and 2hours respectively following administration of caffeine. Caffeine at a dose of 25 mg/kg and 100 mg/kg produced significant (P<0 .05="" 0.05="" 100="" 25mg="" 2="" a="" administration="" after="" all="" although="" and="" animal="" animals.="" animals="" at="" be="" blood="" body="" caffeine="" can="" causes="" changes="" compared="" comparison="" concluded="" control.="" control="" dependent.="" diabetic="" difference="" dose="" duration="" experiment="" found="" glucose="" group.="" groups.="" groups="" hours="" in="" increase="" increases="" indices="" it="" kg="" lasted="" level="" levels="" lipid="" may="" mg="" no="" of="" on="" other="" produce="" profile="" rats.="" rats="" received="" results="" showed="" significant="" significantly="" span="" suggest="" that="" the="" there="" therefore="" these="" those="" to="" triglyceride="" triglycerides="" was="" weeks="" weights="" wistar="" with="">

CHAPTER ONE

1.0 INTRODUCTION

1.1 Diabetes Mellitus

Excessive urine excretion is one of the major symptoms of diabetes. The most common form of diabetes is diabetes mellitus, a metabolic disorder in which there is an inability to oxidize carbohydrate due to disturbances in insulin function. Diabetes mellitus is characterized by elevated glucose in the plasma and episodic ketoacidosis. Additional symptoms of diabetes mellitus include polydipsia, glucosuria, polyuria, lipemia and hunger (King et al., 1998; WCPD, 2012).

Diabetes mellitus is a heterogeneous clinical disorder with numerous causes. Two main classifications of diabetes mellitus exist, idiopathic and secondary. Idiopathic diabetes is divided into Type 1 diabetes (IDDM) and Type 2 diabetes (NIDDM) (WHO, 2003).

Type 2 diabetes is associated with a cluster of interrelated plasma lipid and lipoprotein abnormalities, including reduced HDL cholesterol, a predominance of small dense LDL particles, and elevated triglycerides. These abnormalities occur in many patients despite normal LDL cholesterol levels. These changes are also a feature of the insulin resistance syndrome (also known as the metabolic syndrome), which underlies many cases of type 2 diabetes. In fact, pre-diabetic individuals often exhibit an atherogenic pattern of risk factors that includes higher levels of total cholesterol, LDL cholesterol, and triglycerides and lower levels of HDL cholesterol than individuals who do not develop diabetes (Krauss, 2004).

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EFFECT OF CAFFEINE ON BLOOD GLUCOSE AND LIPID PROFILE IN ALLOXAN-INDUCED DIABETIC WISTAR RATS

EFFECT OF CAFFEINE ON BLOOD GLUCOSE AND LIPID PROFILE IN ALLOXAN-INDUCED DIABETIC WISTAR RATS

The Complete Research Material is averagely 52 pages long and it is in Ms Word Format, it has 1-5 Chapters. Major Attributes are Abstract, All Chapters, Figures, Appendix, References. Study Level: BTech, BSc, BEng, BA, HND, ND or NCE. Full Access Fee: ₦6,000

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SIMILAR ENGLISH LITERARY STUDIES FINAL YEAR PROJECT RESEARCH TOPICS

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2. INFLUENCE OF INSTRUCTIONAL AIDS ON STUDENTS ACADEMIC ACHIEVEMENT IN ENGLISH LANGUAGE IN SELECTED SECONDARY SCHOOLS IN ZARIA METROPOLIS, KADUNA STATE

3. AN ANALYSIS OF VERBS AND ADVERBIAL PHRASES: USES AND PROBLEMS IN CONTEXUAL GRAMMAR

4. CULTURE AND DISCRIMINATION AGAINST WOMEN IN BUCHI EMECHETA’S THE JOYS OF MOTHERHOOD AND CHIMAMANDA ADICHIE’S PURPLE HIBISCUS

5. LANGUAGE BEHAVIOUR AND ITS EFFECTS IN A MULTILINGUAL SETTING: A SOCIOLINGUISTIC DESCRIPTION OF OGORI/MAGONGO PEOPLE OF KOGI STATE

6. A COMPARATIVE STUDY OF THE SYNTAX OF THE POETRY OF WOLE SOYINKA AND JOE USHIE

7. An assessment of the Problems and Prospects of Translating Hausa Proverbs into English

8. NON-RECEPTION OF ENGLISH AS SECOND LANGUAGE IN ADULTS

9. ENGLISH-BASED LOAN WORDS IN ETUNO LANGUAGE

10. A PRAGMATIC ANALYSIS OF SELECTED YORUBA EUPHEMISMS

Trending Final Year Project Research Topics

The Complete Research Material is averagely 52 pages long and it is in Ms Word Format, it has 1-5 Chapters.

Major Attributes are Abstract, All Chapters, Figures, Appendix, References.

Study Level: BTech, BSc, BEng, BA, HND, ND or NCE.

Full Access Fee: ₦6,000