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ABSTRACT
Diabetes Mellitus (DM) and Thyroid Dysfunction (TD) are the two most common endocrinopathies seen in general population.Type 2 diabetes mellitus(T2DM) is commonly associated with altered thyroid function.The aim of theresearch is to evaluate TD in patients with T2DM attending Endocrinology Clinic of UsmanuDanfodiyo University Teaching Hospital,Sokoto.Blood samples were collected from 80 Type 2 diabetic patients and 80 non diabetic (control) and analyze for fasting blood sugar (FBS), glycatedhemoglobin (HbA1c),thyroid stimulating hormone (TSH),triiodothyrorine (T3),thyroxin (T4), cholesterol, triglycerides (TG), high density lipoprotein (HDL-C)and low density lipoproteins(LDL-C).The levels, of FBS, HbA1c,Cholesterol, TG and LDL-C were observed to be significantly high andthe level of HDL-C was significantly low in diabetics as compared to control(non diabetic patients).The levelsof T3 and T4 weresignificantly low while the level of TSH was significantly high in Type 2 diabetics as compared to non diabetics.Pearson correlation shows a very strong positive relationship between FBS and HbA1c and weak positive relationship between thesesugars and Thyroid hormones(TSH,T3,andT4). Thyroid dysfunction maycomplicates metabolic control in diabetes mellitus (DM).It is therefore patients to recognize and where necessary treat thyroid dysfunction in order to stabilize metabolic control.
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SIMILAR BIOCHEMISTRY FINAL YEAR PROJECT RESEARCH TOPICS
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1. ANALYSIS OF SOME MINERAL CONTENTS OF COCONUT WATER
» CHAPTER ONE INTPDUCTION Background of the Study The coconut (Cocos nucifera L.) is a tropical plant which belongs to the order Arecales and family Are...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages |
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2. EXTRACTION, CHARACTERIZATION AND ANTI-MICROBIAL SCREENING OF WHITE STAR APPLE Crysophyllum albidum SEED OIL
» ABSTRACT Crysophylum albidum oil was extracted from its seed. The percentage yield was 2.56%. The characterization of the oil showed showed that the r...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages |
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3. ASSESSMENT OF THE RELATIONSHIP BETWEEN FOETAL HAEMOGLOBIN LEVELS, MARKERS OF TISSUE DESTRUCTION AND DISEASE SEVERITY IN INDIVIDUALS WITH SICKLE CELL ...
» ABSTRACT Sickle cell Anaemia is a genetic disorder that leads to the production of Sickle haemoglobin, whichresults in abnormal functions of the red b...Continue Reading »Item Type & Format: Project Material - Ms Word | 72 pages |
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4. UREA AND CREATININE CONCENTRATIONS OF PLASMODIUM BERGHEI INFECTED MICE TREATED WITH COARTEM, HIPPROCRATEA AFRICANA ROOT BARK EXTRACT, CIPROFLOXACIN AN...
» ABSTRACT The concomitant effect of Hippocratea africana root bark extract, Jatropha tanjorensis Ciprofloxacin and Coartem on markers (Urea and Creatin...Continue Reading »Item Type & Format: Project Material - Ms Word | 57 pages |
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5. EXTRACTION AND CHARACTERIZATION OF VEGETABLE OIL USING BREAD FRUIT SEED.
» 1.1 Vegetable oil A vegetable oil is a triglyceride extracted from a plant. Such oils have been part of human culture for millennia. The term "vegetab...Continue Reading »Item Type & Format: Project Material - Ms Word | 37 pages |
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6. EFFECTS OF DIFFERENT TYPES OF ORGANIC FERTILIZERS ON GROWTH PERFORMANCE, NUTRIENTS AND TOXICOLOGICAL COMPOSITION OF AMARANTHUS CAUDATUS AND AMARANTHUS...
» Abstract The objective of this study is to evaluate the effect of different types organic fertilizers on growth performance, nutrient and toxicologica...Continue Reading »Item Type & Format: Project Material - Ms Word | 152 pages |
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7. COMPREHENSIVE THEORETICAL COMPARATIVE STUDY ON CUBIC AND MONOCLINIC LATTICE OF WO3 USING DFT AS IMPLEMENTED IN QUANTUM ESPRESSO
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8. A STUDY OF THE PHARMACOLOGICAL EFFECTS OF METHANOL EXTRACT OF RIPE AND UNRIPE PLANTAIN
» INTRODUCTION 1.1 Background to Study Natural products, such as plants extract, either as pure compounds or as standardized extracts, provi...Continue Reading »Item Type & Format: Project Material - Ms Word | 70 pages |
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9. EFFECT OF PROCESSING (TOASTING AND FERMENTATION) ON THE NUTRITIONAL VALUE OF SICKLE POD (Senna obtusifolia) SEEDS
» ABSTRACT The effects of fermentation and toasting on the nutrients and antinutrients composition of Senna obtusifoliai seeds were investigated. Senna ...Continue Reading »Item Type & Format: Project Material - Ms Word | 112 pages |
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10. BRAIN ANTIOXIDANT ACTIVITIES OF SIX ARTEMISININ-BASED COMBINATION THERAPIES (ACTs) IN EXPERIMENTAL MALARIA MODEL
» ABSTRACT Malaria parasite has remained a menace to human immune system as it usually subjects its host to oxidative stress which in turn has an effect...Continue Reading »Item Type & Format: Project Material - Ms Word | 78 pages |
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