ABSTRACT

Diabetes Mellitus (DM) and Thyroid Dysfunction (TD) are the two most common endocrinopathies seen in general population.Type 2 diabetes mellitus(T2DM) is commonly associated with altered thyroid function.The aim of theresearch is to evaluate TD in patients with T2DM attending Endocrinology Clinic of UsmanuDanfodiyo University Teaching Hospital,Sokoto.Blood samples were collected from 80 Type 2 diabetic patients and 80 non diabetic (control) and analyze for fasting blood sugar (FBS), glycatedhemoglobin (HbA1c),thyroid stimulating hormone (TSH),triiodothyrorine (T3),thyroxin (T4), cholesterol, triglycerides (TG), high density lipoprotein (HDL-C)and low density lipoproteins(LDL-C).The levels, of FBS, HbA1c,Cholesterol, TG and LDL-C were observed to be significantly high andthe level of HDL-C was significantly low in diabetics as compared to control(non diabetic patients).The levelsof T3 and T4 weresignificantly low while the level of TSH was significantly high in Type 2 diabetics as compared to non diabetics.Pearson correlation shows a very strong positive relationship between FBS and HbA1c and weak positive relationship between thesesugars and Thyroid hormones(TSH,T3,andT4). Thyroid dysfunction maycomplicates metabolic control in diabetes mellitus (DM).It is therefore patients to recognize and where necessary treat thyroid dysfunction in order to stabilize metabolic control.

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