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ABSTRACT
Diabetes Mellitus (DM) and Thyroid Dysfunction (TD) are the two most common endocrinopathies seen in general population.Type 2 diabetes mellitus(T2DM) is commonly associated with altered thyroid function.The aim of theresearch is to evaluate TD in patients with T2DM attending Endocrinology Clinic of UsmanuDanfodiyo University Teaching Hospital,Sokoto.Blood samples were collected from 80 Type 2 diabetic patients and 80 non diabetic (control) and analyze for fasting blood sugar (FBS), glycatedhemoglobin (HbA1c),thyroid stimulating hormone (TSH),triiodothyrorine (T3),thyroxin (T4), cholesterol, triglycerides (TG), high density lipoprotein (HDL-C)and low density lipoproteins(LDL-C).The levels, of FBS, HbA1c,Cholesterol, TG and LDL-C were observed to be significantly high andthe level of HDL-C was significantly low in diabetics as compared to control(non diabetic patients).The levelsof T3 and T4 weresignificantly low while the level of TSH was significantly high in Type 2 diabetics as compared to non diabetics.Pearson correlation shows a very strong positive relationship between FBS and HbA1c and weak positive relationship between thesesugars and Thyroid hormones(TSH,T3,andT4). Thyroid dysfunction maycomplicates metabolic control in diabetes mellitus (DM).It is therefore patients to recognize and where necessary treat thyroid dysfunction in order to stabilize metabolic control.
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SIMILAR BIOCHEMISTRY FINAL YEAR PROJECT RESEARCH TOPICS
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1. COMPARATIVE QUANTITATIVE PHYTOCHEMICAL ANALYSIS OF ETHANOL EXTRACT OF Gongronema latifolium AND Allium sativum
» TABLE OF CONTENTS Cover page Title page Certification i Dedication ii Acknowledgement iii Abstract iv Table of content V List of tables vi CHAPTER ONE...Continue Reading »Item Type & Format: Project Material - Ms Word | 44 pages |
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2. DETERMINATION OF PHYTIC ACID CONTENT, OXALATE CONTENT, TANNIN CONTENT AND CYANIDE CONTENT IN TEN EDIBLE SEEDS
» ABSTRACT Antrinutitional factors re compounds which reduce the nutrient utilization or food intake of plant or plant products (seeds) used as human fo...Continue Reading »Item Type & Format: Project Material - Ms Word | 63 pages |
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3. Garcinia kola Heckel STEM BARK ETHANOLIC EXTRACT AND ITS TRITERPENOID FRACTION PROTECTED AGAINST SODIUM ARSENITE-INDUCED HEPATOTOXICITY AND NEPHROTOXI...
» ...Continue Reading »Item Type & Format: Project Material - Ms Word | 154 pages |
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4. VARIABILITY AND CORRELATION STUDIES IN BASIL SCENT LEAF (Ocimum gratissimum)
» CHAPTER ONE INTRODUCTION Diabetes mellitus is a syndrome of impaired carbohydrate, fat and protein metabolism caused by either lack of insulin secreti...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages |
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5. EFFECTS OF DIFFERENT TYPES OF ORGANIC FERTILIZERS ON GROWTH PERFORMANCE, NUTRIENTS AND TOXICOLOGICAL COMPOSITION OF AMARANTHUS CAUDATUS AND AMARANTHUS...
» Abstract The objective of this study is to evaluate the effect of different types organic fertilizers on growth performance, nutrient and toxicologica...Continue Reading »Item Type & Format: Project Material - Ms Word | 152 pages |
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6. BIOCHEMISTRY OF GOUT
» CHAPTER ONE INTRODUCTION 1.1 Introduction Gout was described by Hippocrates as “the disease of kings” due to its association with rich diet. (Fala...Continue Reading »Item Type & Format: Project Material - Ms Word | 31 pages |
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7. PHYTOCHEMICAL ANALYSIS OF SELECTED TOMATO PRODUCTS
» CHAPTER ONE 1.0 INTRODUCTION Intake of tomato and tomato based products contributes to the absorption of a wide range of carotenoids in human serum an...Continue Reading »Item Type & Format: Project Material - Ms Word | 74 pages |
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8. A PROJECT RESEARCH INTO SERUM CALCIUM LEVEL IN GERIATRIC MEN, COMPERATIVE STUDIES
» ABSTRACT Calcium is the most important mineral in the body. The body needs calcium for normal functioning of nerves and muscles including the most imp...Continue Reading »Item Type & Format: Project Material - Ms Word | 50 pages |
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9. EFFECT OF METHANOLIC LEAF EXTRACT OF ACALYPHA WILKESIANA ON WEIGHT PARAMETERS IN PARACETAMOL INDUCED HEPATOXICITY IN MALE WISTAR RATS RATS
» ABSTRACT The potential effect of methanolic extract of the leaves of Acalypha wilkesiana on the weight of wistar rats was investigated. Calculated amo...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages |
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10. EFFECTS OF ETHANOL LEAVES EXTRACT OF Jatropha tanjorensis ON RENAL FUNCTION OF MALE ALBINO WISTAR RATS
» ABSTRACT This study is aimed at investigating effects of ethanol leaves extract of Jatropha tanjorensis on renal function of male albino wistar rats. ...Continue Reading »Item Type & Format: Project Material - Ms Word | 59 pages |
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