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ABSTRACT
This study evaluated the activity of antilipemic
water extracts from leaves of Desmodium velutinum albino Wistar rats.
Phytochemical analysis of leaf extract showed the presence of tannins,
saponins, alkaloids, soluble carbohydrates, flavonoids, reducing sugars,
steroids, cyanide and terpenes. Animals were treated with drugs known
(2ml atorvastatin). There were lots of HDL reductions 13.00 1.41 mg / dL
LDL 1.20 0.14 mg / dl and triglycerides 39.00 0.14 mg / dl, compared to
extract the Desmodium velutinum water (0.5ml). when administered was
found to significantly reduce plasma lipids LDL was 1.90 0.00mg / dl,
triglyceride 50.00 0.00mg / dl and raise HDL 25.00 0.00 mg / dl, which
is the good cholesterol. The aqueous extract of Desmodium velutinum
sheet can optionally normalize plasma lipids compared to atorvastatin
given group. The analysis of phytochemicals showed that the association
between these compounds and complexes and other components play an
important role in the biological activity of the sheet. This study
suggests that the D.velutinum aqueous extract of leaves have
lipid-lowering effect and the antilipidemic.
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