Physiology Final Year Project Research Topics

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LIST OF PHYSIOLOGY PROJECT TOPICS AND MATERIALS
S/N Project Topic
1

EFFECTS OF CLOVE (SYZYGIUM AROMATICUM) AND FERMENTED GINGER (ZINGIBER OFFICINALE) SUPPLEMENTATIONS ON SOME PHYSIOLOGICAL PARAMETERS IN HIGH FAT DIET-I...

Abstract The evaluation of makers for characterized underlined pathologies in diabetes mellitus isuseful in prevention, monitoring and management of the disease. This studyaimed to investigate the effects of clove buds and fermented ginger rhizome supplements onblood glucose, insulin, insulin receptor, leptin levels, Lipid profile, thyroid hormones, thyroid stimulating hormone (TSH) concentrations... Continue Reading »

Item Type & Format: Project Material - Ms Word |  148 pages |  Instant Download  |  Chapter 1-5  |  PHYSIOLOGY DEPARTMENT

2

STUDY OF THE EFFECTS OF AZADIRACTA INDICA SEED EXTRACT ON BLOOD GLUCOSE LEVELS OF NORMOGLYCEMIC AND STREPTOZOCIN-INDUCED DIABETIC WISTAR RATS.

ABSTRACT This study investigated the effects of Azadiracta Indica seed extract on blood glucose levels of streptozocin induced diabetic and normoglycemic Wistar rats. An acute toxicity studies of the extract Azadiracta Indica was done, the result of the acute toxicity study showed that the extract had an LD50 3000mg/kg bodyweight via intraperitoneal route in Wistar rats. A preliminary phytochemica... Continue Reading »

Item Type & Format: Project Material - Ms Word |  195 pages |  Instant Download  |  Chapter 1-5  |  PHYSIOLOGY DEPARTMENT

3

EFFECT OF ETHANOL EXTRACT OF BRASSICA OLERACEA (CABBAGE) ON INTESTINAL MOTILITY AND GASTRIC SECRETION IN ALBINO WISTAR RATS

ABSTRACT The effect of ethanol extract of Brassica oleracea (cabbage) on intestinal motility and gastric secretion was studied using wistar albino rat. Acute toxicity of the plant was carried out using Lorke’s method. 15 mice were used for LD50. They were divided into five groups of three animals each and they were zero percent mortality at the dose of 5,000ml/kg which was determined as the LD50... Continue Reading »

Item Type & Format: Project Material - Ms Word |  79 pages |  Instant Download  |  Chapter 1-5  |  PHYSIOLOGY DEPARTMENT

4

LOCALITY AND GENDER AS PREDICTORS OF ATTRIBUTION OF SUCCESS

ABSTRACT This study investigated whether locality and gender will significantly predict attribution of success among adolescents. The participants were selected from Community secondary School Agbani and Federal Government College Enugu. The participants were randomly selected making use of simple random sampling technique and were in Senior Secondary I and II of the schools. The participants were... Continue Reading »

Item Type & Format: Project Material - Ms Word |  52 pages |  Instant Download  |  Chapter 1-5  |  PHYSIOLOGY DEPARTMENT

5

EFFECT OF OMEGA 3 FATTY ACIDS AND VITAMIN A ON CARRAGEENAN INDUCED JOINT INFLAMMATION IN FEMALE WISTAR RATS

Abstract Joint inflammation is a hallmark of diseases such as arthritis affecting single or multiple joints associated with increased pro inflammatory markers and free radicals. Efforts are channeled towards discovering therapeutic agents which are more effective, less toxic with prolonged use and more affordable.The aim of this study was to investigate the effect of omega 3 fatty acids and vitami... Continue Reading »

Item Type & Format: Project Material - Ms Word |  100 pages |  Instant Download  |  Chapter 1-5  |  PHYSIOLOGY DEPARTMENT

6

HYPOGLYCEMIC AND HEPATO-PROTECTIVE EFFECTS OF HYDRO-ETHANOL SILK OF ZEA-MAYS EXTRACT ON ALLOXAN-INDUCED DIABETIC WISTAR RATS

ABSTRACT Globally, as of 2010, an estimated 285 million people had diabetes, with type 2 making up about 90% of the cases The management of diabetes without side effects is a major challenge in the medical system.Silkof Zea maysfrom a variety of maize sources has been shown to have a range of biological activities and potential health benefits such as hypoglycemia, antioxidant, hypocholesteromic a... Continue Reading »

Item Type & Format: Project Material - Ms Word |  105 pages |  Instant Download  |  Chapter 1-5  |  PHYSIOLOGY DEPARTMENT

7

PSYCHOSOCIAL FACTORS INFLUENCING COMMERCIAL DRIVERS RECKLESSNESS

CHAPTER ONE 1.1 Background to the Study Driving a car, bus, lorry or an articulated vehicle is a psychomotor activity that requires a combination of concentration and good visual and auditory functions. Several forces that can negatively affect driving mostly fall within the purview of psycho social factors (Kagashe and Seleman, 2009). Some of these psychosocial factors are the use of alcohol and ... Continue Reading »

Item Type & Format: Project Material - Ms Word |  58 pages |  Instant Download  |  Chapter 1-5  |  PHYSIOLOGY DEPARTMENT

8

EVALUATION OF ANTICONVULSANT ACTIVITY OF DATE (PHOENIX DACTYLIFERA) IN MICE AND CHICKS

ABSTRACT Phoenix dactylifera contains some phytochemical constituents which have been reported to be associated with different pharmacological activities. Triterpenes and steroids, flavonoids, cardiac glycoside among other phytochemicals have been reported to possess anticonvulsant activity. This study therefore is aimed at evaluating the anticonvulsant activity of aqueous extract of Phoenix dacty... Continue Reading »

Item Type & Format: Project Material - Ms Word |  75 pages |  Instant Download  |  Chapter 1-5  |  PHYSIOLOGY DEPARTMENT

9

PEAK EXPIRATORY FLOW RATE AND SOME ASPECT OF ECG AND HAEMATOLOGICAL VARIABLES IN NON-PREGNANT AND PREGNANT WOMEN AT SECOND AND THIRD TRIMESTERS OF PRE...

ABSTRACT Values of peak expiratory rate (PEFR), ECG and Haematological variables in 250 females at their reproductive ages, made up of 123 pregnant subjects and 127 non pregnant control groups, living and/or working in Kura local government area and its environs were obtained. Pearson’s correlation coefficient between PEFR and ages as well as ECG, Haematological and other anthropometric meas... Continue Reading »

Item Type & Format: Project Material - Ms Word |  86 pages |  Instant Download  |  Chapter 1-5  |  PHYSIOLOGY DEPARTMENT

10

EFFECT OF RESVERATROL ON CHLORPYRIFOS-INDUCED COGNITIVE IMPAIRMENT IN SWISS ALBINO MICE

ABSTRACT Chlorpyrifos (CPF) is thought to cause oxidative injury in both humans and animals via the formation of free radicals. Exposure to CPF at doses that did not result in overt clinical symptoms has been reported among pesticide applicators and other farm workers thereby constituting an important source of occupational hazards to these groups of individuals. Chlorpyrifos (CPF) has been associ... Continue Reading »

Item Type & Format: Project Material - Ms Word |  97 pages |  Instant Download  |  Chapter 1-5  |  PHYSIOLOGY DEPARTMENT

11

ANTHROPOMETRIC AND REPRODUCTIVE CHARACTERISTICS OF GIRLS AND WOMEN IN KUMANA CHIEFDOM, KAURU LOCAL GOVERNMENT AREA OF KADUNA STATE, NIGERIA

ABSTRACT The leaves ofZiziphus mauritiana have been reported to be used in the management of depressive illnesses in traditional medicine. The antidepressant activity of the methanol leaf extract of the plant was evaluated using tail suspension test (TST) and forced swim test (FST) at the doses of 25, 50, 100, and 200 mg/kg.Imipramine (20mg/kg) was used as standard antidepressant drug.The effect o... Continue Reading »

Item Type & Format: Project Material - Ms Word |  109 pages |  Instant Download  |  Chapter 1-5  |  PHYSIOLOGY DEPARTMENT

12

EFFECT OF ETHANOL EXTRACT OF ZINGIBER OFFICINALE (GINGER) AND MUCUNA URENS (HORSE EYE-BEAN) ON TESTOSTERONE IN MALE ALBINO RATS.

ABSTRACTS The effects of ethanol extract of Ginger and Horse eye bean on testosterone of male albino wistar rats were investigated. Fifty male albino rats weighing 120g – 200g were divided into 10 groups with 5 animals in each group. Group I served as the control while Groups 2,3,4,5,6,7,8,9,10 were the experimental groups. 600 seeds of Mucana urens and 200 rhizome of Zingiber officinale were us... Continue Reading »

Item Type & Format: Project Material - Ms Word |  47 pages |  Instant Download  |  Chapter 1-5  |  PHYSIOLOGY DEPARTMENT

13

EVALUATION OF THE EFFECT OF CAMEL MILK ON PHYSIOLOGICAL PARAMETERS OF POLOXAMER 407 INDUCED HYPERLIPIDEMIC WISTAR RATS

ABSTRACT Hyperlipidemia is viewed as a primary mediator of cardiovascular disease. The aim of the study is to evaluate the effect of camel milk on Poloxamer 407 induced hyperlipidemic Wistar rats. Thirty adult male Wistar rats weighing between 150 200g were randomly assigned into six groups of five animals each; Group I: administered distilled water, Group II: Hyperlipidemic negative control, Grou... Continue Reading »

Item Type & Format: Project Material - Ms Word |  90 pages |  Instant Download  |  Chapter 1-5  |  PHYSIOLOGY DEPARTMENT

14

MODULATORY ROLE OF RESVERATROL-INDUCED DIETARY RESTRICTION AND ENVIRONMENTAL ENRICHMENT ON NEUROBEHAVIOURAL OUTCOME IN YOUNG HEALTHY MICE

ABSTRACT Dietary Restriction (DR) otherwise known as Caloric Restriction (CR) has been generally defined as consumption of nutritious diet that is 30% to 40% less in calories compared to ad libitum diet while Environmental Enrichment (EE) is defined as a sustained and progressive increase in cognitive and sensorimotor stimuli with aggregated voluntary physical activity and complex social interacti... Continue Reading »

Item Type & Format: Project Material - Ms Word |  144 pages |  Instant Download  |  Chapter 1-5  |  PHYSIOLOGY DEPARTMENT

15

PHYTOCHEMICAL SCREENING OF AQUEOUS AND ETHANOLIC LEAVES EXTRACTS OF COSTUS AFER AND THEIR EFFECTS ON LIPID PROFILE OF FEMALE ALBINO WISTAR RATS

ABSTRACT Medicinal plants contain bioactive compounds capable of preventing and fighting cardiovascular related disease. These compounds must be screened and assayed before effective drugs are developed. Thus, the phytochemical constituents of aqueous and ethanolic leaves extracts of Costus afer and their effects on lipid profile of female albino wistar rats were determined. The results of the phy... Continue Reading »

Item Type & Format: Project Material - Ms Word |  52 pages |  Instant Download  |  Chapter 1-5  |  PHYSIOLOGY DEPARTMENT

16

INFLUENCE OF JOB INVOLVEMENT, ORGANIZATIONAL COMMITMENT AND EMPLOYEE STRESS ON PSYCHOLOGICAL WELL BEING OF CIVIL SERVANTS IN UYO METROPOLIS

ABSTRACT The purpose of this study was to examine the influence of job involvement, organizational commitment and employee stress on psychological wellbeing of civil servants. The sample consisted of three hundred and ten (310) respondents (145 males and 165 females with the mean age of 35.32 and a standard deviation of 7.27), who were selected using simple random sampling technique from the minis... Continue Reading »

Item Type & Format: Project Material - Ms Word |  52 pages |  Instant Download  |  Chapter 1-5  |  PHYSIOLOGY DEPARTMENT

17

EFFECT OF VITAMIN E AND RESVERATROL ON OXIDATIVE STRESS AND HAEMATOLOGICAL PARAMETERS OF CARBAMAZEPINE-INDUCED OXIDATIVE STRESS IN MALE WISTAR RATS

ABSTRACT Carbamazepine (CBZ) is a drug used in the treatment of epilepsy and neuropathic pain. Carbamazepine induces oxidative stress and haematological toxicity. Resveratrol, known as 3,5,4′ trihydroxystilbene, is found in grapes and other plant products. Resveratrol effectively scavenges free radicals and other oxidants. Vitamin E a lipid soluble antioxidant present in all cellular membran... Continue Reading »

Item Type & Format: Project Material - Ms Word |  89 pages |  Instant Download  |  Chapter 1-5  |  PHYSIOLOGY DEPARTMENT

18

INFLUENCE OF GENDER AND LOCALITY ON THE ATTITUDE OF ADOLESCENTS TOWARDS AIDS

ABSTRACT This study investigated Influence of Gender and Locality on the Attitude of Adolescent Towards ADIS. 100 were Adolescent randomly selected from urban and rural area for the study. The age range was between 15 19 years with a mean age of 17years. Attitude towards AIDS scale Comoluabi 1995 was used for data collection. 2´2 factorial design was used and a two way ANOVA was also adopted... Continue Reading »

Item Type & Format: Project Material - Ms Word |  52 pages |  Instant Download  |  Chapter 1-5  |  PHYSIOLOGY DEPARTMENT

19

EVALUATION OF PROLONGED ADMINISTRATION OF ARTEMETHER-LUMEFANTRINE ON SPERM INDICES AND TESTICULAR BIOMARKERS OF OXIDATIVE STRESS IN MALE WISTAR RATS: ...

ABSTRACT There is frequent use of artemisinin based combination therapies (ACTs) due to recurrence of malaria infection in Nigeria. The ACTs generate free radicals as part of their mode of action. Reactive oxygen species have been implicated in the etiology of male infertility. In this study, the effect of prolonged administration of artemether lumefantrine (AL) and the ameliorative effect of vita... Continue Reading »

Item Type & Format: Project Material - Ms Word |  104 pages |  Instant Download  |  Chapter 1-5  |  PHYSIOLOGY DEPARTMENT

20

PROTECTIVE EFFECT OF VITAMIN E ON ENDOSULFAN-INDUCED OXIDATIVE CHANGES AND ASSOCIATED NEUROBEHAVIOURAL DEFICIT IN MALE WISTAR RATS

ABSTRACT Endosulfan is an organochlorine pesticide commonly used to control pests in vegetables, cotton, fruits and other agricultural produce. It is a contact and stomach insecticide toxic to mammals, fish and other aquatic organisms. Several reports have shown that it is a highly neurotoxic agent. The aim of this study was to evaluate the role of brain lipoperoxidation and oxidative stress in se... Continue Reading »

Item Type & Format: Project Material - Ms Word |  137 pages |  Instant Download  |  Chapter 1-5  |  PHYSIOLOGY DEPARTMENT

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