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ABSTRACT
Aim: To evaluate the anti-diabetic effect of aqueous extract of Saccharum officinarum (stem bark) in the genomic DNA of diabetic Wistar rats.
Methodology: 15 Streptozotocin-induced diabetic male rats and five non diabetic rats were randomly and evenly distributed into four groups, and were subsequently exposed to the following treatments for 14 days: Group I (Control): Distilled water (1ml/kg B.W); Group II: Normal saline (1ml/kg B.W); Group III: treated Diabetic rats (Metformin) (500mg/kg B..W); Group IV: Diabetic rats treated with Saccharum officinarum (stem bark) (500mg/Kg B.W). Administration was done orally for 14 days. Body weight changes were analyzed by induction of obesity through high fat diet. Diabetes type 2 was induced using Streptozotocin injected intraperitoneally (40mg/kg B.W). The serum fasting blood glucose was analyzed using the glucose test kits (AGGAPPE). The liver tissue from each group was randomly selected and analyzed using the Nano drop spectrophotometric analysis.
Result: The body weight of the rats were significant after twelve weeks of high fat diet (p< 0.05). Fasting blood glucose level changes in diabetic treated rats (p<0.002), there were changes in genomic DNA yield and purity in the diabetic treated rats (p<0.05)
Conclusion: The aqueous extract of the plant showed anti-diabetic potentials by decrease in the fasting blood glucose level and causing significant changes in genomic DNA quality and quantity.
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SIMILAR BIOLOGY FINAL YEAR PROJECT RESEARCH TOPICS
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1. SURVEY OF PLANTS USED IN BEAUTY CARE AMONG THE FULANIS IN WAMAKKO LOCAL GOVERNMENT AREA OF SOKOTO STATE
» ABSTRACT An ethnobotanical study of plants used in beauty care among the Fulani tribes uin Wamakko Local Government Area of Sokoto State was conducted...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages | Instant Download | Chapter 1-5 | BIOLOGY DEPARTMENT
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2. Effect of Alectra vogelii (Benth) Aqueous Extract on the Growth of Cowpea [Vigna unguiculata (L.) Walp] Varieties
» ABSTRACT Experimentswere conducted to evaluate the effect of Alectra vogelii (Benth) aqueous extract on the growth of cowpea (Vigna unguiculata (L.) W...Continue Reading »Item Type & Format: Project Material - Ms Word | 96 pages | Instant Download | Chapter 1-5 | BIOLOGY DEPARTMENT
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3. AN INVESTIGATIVE STUDY ON THE VIEWS OF BIOLOGY STUDENTS ON THE PROBLEMS OF LABORATORY MANAGEMENT AND SAFETY IN SECONDARY SCHOOLS
» CHAPTER ONE INTRODUCTION 1.1 Background of the study Safety practice can be explained to mean the process of averting danger. According to advance lea...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages | Instant Download | Chapter 1-5 | BIOLOGY DEPARTMENT
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4. AN INVESTIGATIVE STUDY ON THE VIEWS OF BIOLOGY STUDENTS ON THE PROBLEM OF LABORATORY MANAGEMENT AND SAFETY IN SECONDARY SCHOOLS
» ABSTRACT The purpose of this study is to find out the biology Teachers views on problems of laboratory management and safety in selected secondary sch...Continue Reading »Item Type & Format: Project Material - Ms Word | 22 pages | Instant Download | Chapter 1-5 | BIOLOGY DEPARTMENT
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5. ECONOMIC IMPORTANCE OF PTERIDOPHYTES
» TABLE OF CONTENTS Cover Page i Certification ii Dedication iii Acknowledgements iv Table of Content v Summary vii CHAPTER ONE 1.0 Introduction 1 Chapt...Continue Reading »Item Type & Format: Project Material - Ms Word | 37 pages | Instant Download | Chapter 1-5 | BIOLOGY DEPARTMENT
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6. ISOLATION AND IDENTIFICATION OF FUNGI SPOILAGE AND ORGANISMS IN PACKAGED AND UNPACKAGED MILK, SOYBEAN FLOUR AND CORN FLOUR
» CHAPTER ONE INTRODUCTION Food products are a rich nutrient source that can attract both bacterial and fungal colonizers. Pitt et al (2009). As such, t...Continue Reading »Item Type & Format: Project Material - Ms Word | 43 pages | Instant Download | Chapter 1-5 | BIOLOGY DEPARTMENT
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7. COMBINED EFFECT OF ETHANOL EXTRACT OF Mucuna urens (HORSE-EYE BEANS SEED) AND ETHANOL EXTRACT OF Zingiber officinale (GINGER RHIZOME) ON SPERM MOTILI...
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8. RELATIONSHIP BETWEEN ANAEMIA, SOD AND G6PD DEFICEINCY ON SICKLE CELL PATIENTS
» ABSTRACT The relationship between anemia, SOD (superoxide dismutase) and G6PD (glucose 6 phosphate) in SCD (sickle cell disease) patients were determi...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages | Instant Download | Chapter 1-5 | BIOLOGY DEPARTMENT
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9. THE EFFECTIVENESS OF INSTRUCTIONAL MATERIALS IN TEACHING AND LEARNING BIOLOGY IN SENIOR SECONDARY SCHOOL
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10. BIOLGICAL WASTE WATER TREATEMENT IN NIGERIA
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