Zika virus disease is a mosquito-borne disease caused by Zika virus which causes in general a mild febrile illness with maculopapular rash. Aedes mosquitoes are considered as main vectors. Zika virus infection, at present, is one of the greatest concerns of medical personnels. Though it has been reported for quite a longtime, its rapid emergence, new modes of transmission, and more importantly, the new modes of transmission, and more importantly, the congenital anomalies associated with it have made the situation worse. It was first detected in 1947. After that, this infection was found in the countries of Africa as well as Asia. At present, interestingly it has been reported from Brazil. Microcephaly and intracranial calcification have been postulated to be related to maternal infection with this virus. Though it is asymptomatic in maximum number of cases, the serious complications of the infection should be prevented at the earliest. No specific treatment and vaccine are available till now.       TABLE OF CONTENTS    Title page -    - - - - - - - -- - - i  Certification - - - - -- - - - - - -ii  Dedication - - - - - - - -- - - -iii   Acknowledgement - - -- - - - - - - iv  Table of contents - - - - - - - - - - v  Abstract - - - - - - - - - - - -vi  Introduction - -- - - - - - - - -1  Objectives - - - - - - - - - -3  Concept of Zika virus infection - - - - - - - -4  Historical perspective: From 1947 -2016  - - - - - - -8  Zika virus infection: A current global threat to maternal and child health - - -10  The role of national authorities and individuals in the prevention and control of Zika virus infection - - - - - - - - - - -15  The role of health professionals in the prevention of Zika virus Infection - --- -18  Conclusion/Summary - - - - - - - - - -22  Recommendations - - - - - - - - -23  References - - - - - - - - - - -24

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