- The Complete Research Material is averagely 50 pages long and it is in Ms Word Format, it has 1-5 Chapters.
- Major Attributes are Abstract, All Chapters, Figures, Appendix, References.
- Study Level: BTech, BSc, BEng, BA, HND, ND or NCE.
- Full Access Fee: ₦6,000
Get the complete project »
ABSTRACT
Destabilization of Lysozyme and chaperone like action of alpha crystallin isolated from goat’s eye lens was investigated at various temperature ranges in phosphate buffer (pH 7.1) solution and dithiothretol (DTT). This was monitored spectrophotometrically at 260nm. The heat and DTT-induced destabilization of lysozyme was prevented by alpha crystallin in a concentration dependent manner. Alpha crystallin like other chaperones, fulfils its chaperone like action in preventing aggregation of denatured proteins by the formation of complexes.
CHAPTER ONE
1.0 INTRODUCTION AND LITERATURE REVIEW
1.1 INTRODUCTION
Proteins are the workhorses of the living cell. Although proteins may differ in sequence, shape and function, but have in common, the same stereo configuration (i.e. they all have to fold into specific three-dimensional structures) which are mandatory for proper function (Bruce et al., 2002). Protein structures however are not rigid, but have a dynamic life style, which may involve unfolding and refolding, complex association and dissociation (Anfisen, 1972). Stress and also many physiological events require proteins to surrender their structure or to regain it at a later stage. A very large number of distinct conformations exist for the polypeptide chain of which a protein spends most of its time in the native conformation, which spans only an extremely small fraction of the entire configuration space. Thus, the amino acid sequence of proteins must satisfy two requirements: one, thermodynamics and the other kinetic. The thermodynamics requirement is that the sequence must have a unique folded conformation, which is stable under physiological conditions.
Most proteins can be denatured by heat, which has complex effect on the weak interactions in proteins (Vandenberg et al., 2000).
If the existing temperature is increased slowly, a protein conformation
generally remains intact until an abrupt loss of structure and function
occurs over a narrow temperature range (Nelson and Cox, 2008). The
spatial arrangement of atoms in a protein is called its conformation
(Deechongkit et al., 2004).
You either get what you want or your money back. T&C Apply
You can find more project topics easily, just search
-
SIMILAR BIOCHEMISTRY FINAL YEAR PROJECT RESEARCH TOPICS
-
1. EFFECTS OF ETHANOLIC ROOT EXTRACT OF UGU OYIBO (Jatropha tanjorensis) ON HAEMATOLOGICAL INDICES OF FEMALE ALBINO WISTAR RAT
» ABSTRACT Jatropha tanjorensis is a natural medicinal herb which has been used over the years in the treatment of many health disorders. This study was...Continue Reading »Item Type & Format: Project Material - Ms Word | 76 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
2. EFFECT OF FRYING AND BOILING ON PHYSICOCHEMICAL PROPERTIES OF OIL
» CHAPTER ONE 1.0 INTRODUCTION Groundnut (Arachis hypogaea) is a leguminous plant grown in Nigeria mainly for its seeds though farmers use its leaves an...Continue Reading »Item Type & Format: Project Material - Ms Word | 24 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
3. COMPREHENSIVE THEORETICAL COMPARATIVE STUDY ON CUBIC AND MONOCLINIC LATTICE OF WO3 USING DFT AS IMPLEMENTED IN QUANTUM ESPRESSO
» CHAPTER ONE 1.0 INTRODUCTION Tungsten (vi) oxide, also known as tungsten trioxide or tungsten analysis, W03 is a chemical com...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
4. THE EFFECT OF KAKA BITTERS ON THE LIPID PROFILE OFWISTAR RATS FED WITH HIGH FAT DIET
» ABSTRACT Kaka bitters like other bitters is claimed to possess a number of folkloric therapeutic effects including lipid lowering effects. However, th...Continue Reading »Item Type & Format: Project Material - Ms Word | 85 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
5. EFFECTS OF ETHANOL LEAVES EXTRACT OF Jatropha tanjorensis ON RENAL FUNCTION OF MALE ALBINO WISTAR RATS
» ABSTRACT This study is aimed at investigating effects of ethanol leaves extract of Jatropha tanjorensis on renal function of male albino wistar rats. ...Continue Reading »Item Type & Format: Project Material - Ms Word | 59 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
6. COMPARATIVE STUDY OF THE ADSORPTION CAPACITIES OF CHEMICALLY AND MICROWAVE SYNTHESIZED ACTIVATED CARBON
» CHAPTER ONE INTRODUCTION 1.1 BACKGROUND OF STUDY Activated carbon, also widely known as activated charcoal or activated coal is a form of carbon which...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
7. BACTERIOLOGICAL QUALITY OF FROZEN CHICKEN SOLD IN GWAGWALADA MARKET
» CHAPTER ONE INTRODUCTION The first consumer right is to have a product of good quality and not constituting any health hazard. Poultry meat products a...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
8. TREATED AND UNTREATED SUYA IN UYO METROPOLIS
» TABLE OF CONTENTS Title Page Cover Page Certification Dedication Acknowledgement Table of Contents Abstract List of Tables List of Figures CHAPTER ONE...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
9. ANTIMICROBIAL AND PHYTOCHEMICAL PROPERTIES OF YOUNGCOCOS NUCIFERA (COCONUT) WATER AND METHALONIC EDXTRACT OF THE YOUNGCOCOS NUCI
» CHAPTER ONE 1.0 INTRODUCTION AND LITERATURE REVIEW 1.1 INTRODUCTION Medicinal plants represent a rich source of antimicrobials and many other drugs. T...Continue Reading »Item Type & Format: Project Material - Ms Word | 52 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT
-
10. EVALUATION OF NUTRITIVE AND NON-NUTRITIVE COMPONENTS AND ANTI-DIABETIC PROPERTIES OF EDIBLE PORTIONS OF Chrysophyllum albidum FRUIT IN STREPTOZOTOCIN-...
» CHAPTER ONE INTRODUCTION 1.1 Background to the Study Dietary control is vital in the management of diabetes. Reports from FAO (1998); WHO and FAO (200...Continue Reading »Item Type & Format: Project Material - Ms Word | 225 pages | Instant Download | Chapter 1-5 | BIOCHEMISTRY DEPARTMENT